Tuesday, July 12, 2011

Medical Researcher Advisory: On-going Intracerebral Hemorrhage Clinical Trial Participation or Case Study Creation Sought For Critical Patient

Brainmapping: Graphic from 2008 research paper Mapping the Structural Core of Human Cerebral Cortex

Flagler Hospital, St. Augustine, FL – Researchers currently conducting intracerebral hemorrhage clinical trials and/or proposing case studies in furtherance of developing more efficacious treatment regimes based on pharmacologic and vitamin E intervention (mitigation of biochemical cascade myelin de-sheathing effect on axonal connectors) immediately post insult, throughout the entire treatment timeframe among other approaches, and requiring additional study subjects are encouraged to contact Myron D. Stokes, Publisher, eMOTION! REPORTS;  and/or Dr. Walter F. Frady,

Patient status: Update 11/22/11:  Patient is now home in  a controlled environment utilizing neuro-trauma isolation protocols involving low noise, low light and with physician and nurse visitation. Melodic intonation therapy is being used for memory/speech stimulation and relaxation. Patient remains on Valproic Acid wherein this legacy anti-seizure/anti-epileptic medication is being used for its recently understood (2010 University of Texas study by Dr. P.K Dash; et al) neuro-protective/new neuronal growth inducing characteristics. This treatment is in conjunction with high dose Vitamin E advocated in a recent (2010) study at Shiraz (Iran) University of Medical Sciences lead by Nuerosurgery resident Dr. Ali Razmkon.  

While verbal communication is not possible at at this time, patient does engage in blink conversation and will move head, fingers and toes on command; suggesting an approximate cognition level of 11.5 on the Glasgow Scale.  Lastly, although outpatient status at Mayo Clinic Jacksonville was kindly directed by neurologists at this facility as of late October, pursuit of case study remains as operative approach.  --

Subject for consideration is in 8th week of critical condition following cerebral hemorrhage on 6/20/11. This is the third bleed for subject with previous events in 2005 and 2007, all of which patient encountered and survived systolic pressure exceeding 300 and diastolic above 150. Additional data available from primary care physician on request.

CT Abstract (Admission): “There is an intraparenchymal hematoma involving the right thalamic region exending into the superior right deep white matter. The hematoma measures approximately 3.5cm x 3.8 cm x 4.0 cm. There is a prominent rim of edema involving the deep white matter of the cerebrum.

“Intraventricular extension is noted with a prominent amount of blood with the right and left lateral ventricles, the third ventricle, the fourth ventricle. There is extension of blood into the peripontine cisterns bilaterally.

“There are probable obstructive hydrocephalic changes when compared to 3/19/11 (Acute ischemic infarct). There is approximate 6 to 8 mm of right to left subfalcine shift. No fractures are evident.”

Complete and current patient summary available from primary care physician on request.



IMPACT Database of Traumatic Brain Injury: Design and Description

Mapping the Structural Core of Human Cerebral Cortex